Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601036 | 0.90 | PPARG (0.68) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4600852 | 0.87 | PPARG (0.65) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4602045 | 0.86 | PPARG (0.71) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4601167 | 0.86 | PPARG (0.69) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3195469 | 0.86 | PPARG (0.78) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4600034 | 0.85 | PPARG (0.73) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4601543 | 0.85 | PPARG (0.67) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4601660 | 0.84 | PPARG (0.64) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4603487 | 0.83 | PPARG (0.79) | PPARGLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4600932 | 0.83 | PPARG (0.78) | PPARGLMNASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |