Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602753 | 0.87 | PPARG (0.64) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3215488 | 0.86 | PPARG (0.69) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL3205117 | 0.85 | PPARG (0.69) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3221791 | 0.85 | PPARG (0.65) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3215799 | 0.84 | PPARG (0.64) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3219568 | 0.84 | PPARG (0.62) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3196887 | 0.83 | PPARG (0.70) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3206523 | 0.82 | PPARG (0.65) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3217520 | 0.81 | PPARG (0.73) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL3214049 | 0.81 | PPARG (0.69) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |