Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 17/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800720 | 0.85 | MKNK2 (0.57) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL2815778 | 0.83 | MKNK2 (0.71) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL3804648 | 0.80 | MKNK2 (0.60) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL3797939 | 0.79 | MKNK2 (0.56) | MKNK2MKNK1 | |
| SCHEMBL3794267 | 0.79 | MKNK2 (0.56) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL3801695 | 0.78 | MKNK2 (0.45) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL3801706 | 0.77 | MKNK2 (0.51) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL13522553 | 0.76 | MAPK14 (0.59) | LMNAPOLBGAAPKM | |
| SCHEMBL4603243 | 0.75 | PIP4K2C (0.45) | MKNK2MKNK1LMNAPOLBGAA | |
| SCHEMBL3795402 | 0.74 | MKNK2 (0.48) | MKNK2MKNK1LMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899353-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DeveloGen Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |