Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 13/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794206 | 0.84 | MKNK2 (0.56) | MKNK2MKNK1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3800432 | 0.83 | MKNK2 (0.51) | MKNK2MKNK1 | |
| SCHEMBL3797693 | 0.81 | MAPK1 (0.44) | MKNK2MKNK1MAPK1GAAHTT | |
| SCHEMBL3802218 | 0.79 | MKNK2 (0.55) | MKNK2MKNK1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3793898 | 0.78 | MAPK1 (0.50) | MKNK2MKNK1MAPK1GAAHTT | |
| SCHEMBL3793904 | 0.78 | MAPK1 (0.50) | MKNK2MKNK1MAPK1GAAHTT | |
| SCHEMBL3799080 | 0.78 | MAPK1 (0.50) | MKNK2MKNK1MAPK1GAAHTT | |
| SCHEMBL3799482 | 0.78 | MKNK2 (0.54) | MKNK2MKNK1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3802152 | 0.77 | MKNK2 (0.63) | MKNK2MKNK1 | |
| SCHEMBL3800028 | 0.76 | MKNK2 (0.55) | MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899353-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DeveloGen Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | claimed |