Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666318 | 1.00 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666210 | 0.86 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2553750 | 0.85 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL29918628 | 0.85 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4603612 | 0.85 | DPP4 (0.55) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL195631 | 0.85 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666762 | 0.85 | DPP4 (0.55) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666277 | 0.84 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4605387 | 0.83 | DPP4 (0.56) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL663961 | 0.83 | DPP4 (0.56) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917001-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007017423-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-15 | — | — | WO | disclosed |
| US-20030130281-A1 | DPP IV inhibitors | HOFFMAN-LA ROCHE INC. | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130281-A1 | DPP IV inhibitors | DPP4, DPP3, DPP7 | DPP4 1/4885DPP7 3/4885DPP8 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.