SCHEMBL4603474

SCHEMBL4603474

CCCCc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.64
RARB P10826 6/20 0.64
ALDH1A1 P00352 5/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 1/20 0.59
PLK1 P53350 1/20 0.59
THRA P10827 1/20 0.57
THRB P10828 1/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
RARA P10276 1/20 0.56
MAPT P10636 1/20 0.56
MTOR P42345 1/20 0.56
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
CNR2 P34972 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31215197 0.98 TRPV1 (0.62) TRPV1RARBALDH1A1HPGDHSD17B10
SCHEMBL11227652 0.95 RARB (0.65) TRPV1RARBALDH1A1THRATHRB
SCHEMBL11239422 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL9721797 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL27845117 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL23014696 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL10997677 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL8924573 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL1534366 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1
SCHEMBL10997930 0.93 RARB (0.66) RARBALDH1A1THRATHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN claimed
EP-1940345-A1 HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION Henkel AG & Co. KGaA (DE) 2008-07-09 EP claimed
WO-2007048486-A1 HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-05-03 WO claimed
US-4145444-A 4-BUTYL-BENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1979-03-20 US claimed
CN-118894771-A Inhibitors of NOTCH1 protein for inhibiting NOTCH1 gene transcription and/or low expression and application thereof 山西医科大学 2024-11-05 CN disclosed
CN-118894771-A Inhibitors of NOTCH1 protein for inhibiting NOTCH1 gene transcription and/or low expression and application thereof 山西医科大学 2024-11-05 CN disclosed
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN disclosed
CN-107709388-B Photocurable resin composition 日产化学工业株式会社 2020-07-07 CN disclosed
WO-2011147311-A1 HYDROXY PROPANEDIOL DERIVATIVES, THEIR PREPARATIVE METHOD, PHARMACEUTICAL COMPOSITIONS AND USE 中国医学科学院药物研究所 (CN) 2011-12-01 WO disclosed
CN-102260178-A Hydroxyl propanediol derivative, its preparation method, its pharmaceutical composition and its purpose 2011-11-30 CN disclosed
CN-102260177-A Propylene glycol derivative, preparation method thereof, pharmaceutical composition thereof and application thereof 2011-11-30 CN disclosed
EP-1940345-A1 HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION Henkel AG & Co. KGaA (DE) 2008-07-09 EP disclosed
US-4145444-A 4-BUTYL-BENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1979-03-20 US disclosed
US-4124726-A 2-FLUORO-4'-ALKYLBENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1978-11-07 US disclosed
US-4082813-A 3-Ioda-α-ethynyl benzhydrol RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1978-04-04 US disclosed
US-4066709-A α-Ethyny benzhydrols RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1978-01-03 US disclosed
US-4051168-A TO FORM FLUOROALKYL AROMATIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US disclosed
US-4042322-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-3980430-A CATIONIC DYE, HALOGENATED HYDROCARBON BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3965179-A BLOCKING, VIRICIDE, FUNGICIDE RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1976-06-22 US disclosed