⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290466 | 0.76 | — | — | |
| SCHEMBL25228817 | 0.72 | — | — | |
| SCHEMBL9796643 | 0.70 | — | — | |
| SCHEMBL2672587 | 0.67 | — | — | |
| SCHEMBL8532418 | 0.67 | — | — | |
| SCHEMBL92092 | 0.67 | — | — | |
| SCHEMBL2671479 | 0.67 | — | — | |
| SCHEMBL1890794 | 0.67 | — | — | |
| SCHEMBL14524591 | 0.67 | — | — | |
| SCHEMBL5468344 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989108-B | Coordinating gene expression using RNA destabilizing elements | 嵌合体生物工程公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-1010684-B1 | PROCESS FOR PRODUCING 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE | KYOWA YUKA KK (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-1676827-A2 | Method for manufacturing 3-alkoxy-2-halogenocyclobutanone derivatives | Kyowa Yuka Co., Ltd. (JP) | 2006-07-05 | — | — | EP | disclosed |
| CN-1258510-C | Process for preparing cyclobutanone derivative | KYOWA YOKA CO LTD (JP) | 2006-06-07 | — | — | CN | disclosed |
| CN-1515535-A | Process for preparing cyclobutanone derivative | Э���ͻ���ʽ���� | 2004-07-28 | — | — | CN | disclosed |
| CN-1134393-C | Preparation method of 3, 4-dihydroxy-3-cyclobutene-1, 2-diketone | ���ʿ����о�����˾ | 2004-01-14 | — | — | CN | disclosed |
| US-6331653-B1 | Process for producing 3,4-dihydroxy-3-cyclobutene-1,2-dione | KYOWA YUKA CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |
| CN-1269778-A | Preparation method of 3, 4-dihydroxy-3-cyclobutene-1, 2-diketone | KYOWA YUKA KK (JP) | 2000-10-11 | — | — | CN | disclosed |
| EP-1010684-A1 | PROCESS FOR PRODUCING 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE | Kyowa Yuka Co., Ltd. (JP) | 2000-06-21 | — | — | EP | disclosed |
| US-4235815-A | N-fluoromethyl-carbamic acid fluorides and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| US-4179465-A | N-fluoromethyl-carbamic acid fluorides and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |