Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 5/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046320 | 1.00 | GRIN2B (0.42) | GRIN2BGRIN2CMEN1MAPTKMT2A | |
| SCHEMBL14262421 | 0.87 | GRIN2B (0.46) | GRIN2BGRIN2CMEN1MAPTKMT2A | |
| SCHEMBL17712395 | 0.80 | GRIN2B (0.51) | GRIN2BGRIN2CCTSL | |
| SCHEMBL17712398 | 0.80 | GRIN2B (0.51) | GRIN2BGRIN2CCTSL | |
| SCHEMBL19627478 | 0.76 | GRIN2B (0.57) | GRIN2BGRIN2CMEN1MAPTKMT2A | |
| SCHEMBL17352433 | 0.76 | GRIN2B (0.57) | GRIN2BGRIN2CMEN1MAPTKMT2A | |
| SCHEMBL19627469 | 0.76 | GRIN2B (0.57) | GRIN2BGRIN2CMEN1MAPTKMT2A | |
| SCHEMBL20293883 | 0.76 | GRIN2B (0.57) | GRIN2BGRIN2CMEN1MAPTKMT2A | |
| SCHEMBL14283166 | 0.75 | AVPR1A (0.40) | CTSLAVPR1ACTSKCTSS | |
| SCHEMBL29557107 | 0.74 | GRIN2B (0.51) | GRIN2BGRIN2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294747-B1 | SYNTHETIC METHODS FOR APLIDINE AND NEW ANTITUMORAL DERIVATIVES, METHODS OF MAKING AND USING THEM | PHARMA MAR SA (ES) | 2008-04-30 | — | — | EP | disclosed |