SCHEMBL4605068

SCHEMBL4605068

O=C(I)CI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodoacetamide SCHEMBL31146774 0.76
Iodoacetamide SCHEMBL1332134 0.76
Iodoacetamide SCHEMBL20371 0.76
SCHEMBL11808604 0.73
Iodoacetamide SCHEMBL25246804 0.73
Iodoacetamide SCHEMBL2361208 0.73
Iodoacetamide SCHEMBL5993617 0.73
Iodoacetamide SCHEMBL29006525 0.73
Iodoacetamide SCHEMBL8333021 0.73
Iodoacetamide SCHEMBL597976 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210206809-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY VERA THERAPEUTICS INC (US) 2021-07-08 US disclosed
US-20210171437-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO VERA THERAPEUTICS INC (US) 2021-06-10 US disclosed
EP-3655388-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO Trucode Gene Repair, Inc. (US) 2020-05-27 EP disclosed
EP-3601237-A2 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY Trucode Gene Repair, Inc. (US) 2020-02-05 EP disclosed
CN-110740994-A Peptide Nucleic Acid (PNA) monomers with orthogonally protected ester moieties 特鲁科德基因修复公司 2020-01-31 CN disclosed
US-20190055190-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO NEUBASE THERAPEUTICS, INC. 2019-02-21 US disclosed
WO-2019018422-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY AND NOVEL INTERMEDIATES AND METHODS RELATED THERETO TRUCODE GENE REPAIR, INC. (US) 2019-01-24 WO disclosed
US-20180282375-A1 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY NEUBASE THERAPEUTICS, INC. 2018-10-04 US disclosed
WO-2018175927-A2 PEPTIDE NUCLEIC ACID (PNA) MONOMERS WITH AN ORTHOGONALLY PROTECTED ESTER MOIETY TRUCODE GENE REPAIR, INC. (US) 2018-09-27 WO disclosed
US-20170145136-A1 RESIN COMPOSITION FOR GOLF BALL AND GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2017-05-25 US disclosed
US-6590123-B2 For cancer theapy MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY 2003-07-08 US disclosed
US-6350431-B1 LIGHT IMAGE CONTRAST AGENT WITH CHROMOPORES LINKED WITH POLYETHER NYCOMED IMAGING AS (NO) 2002-02-26 US disclosed
US-20020022747-A1 Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same BEKESI GEORGE J (US) 2002-02-21 US disclosed
US-6331653-B1 Process for producing 3,4-dihydroxy-3-cyclobutene-1,2-dione KYOWA YUKA CO., LTD. (JP) 2001-12-18 US disclosed
US-6294695-B1 HALOACETOAMIDOBENZOYLUREAS OR ETHYL HALOACETOAMIDOBENZOATES MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK 2001-09-25 US disclosed
CN-1269778-A Preparation method of 3, 4-dihydroxy-3-cyclobutene-1, 2-diketone KYOWA YUKA KK (JP) 2000-10-11 CN disclosed
EP-1010684-A1 PROCESS FOR PRODUCING 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE Kyowa Yuka Co., Ltd. (JP) 2000-06-21 EP disclosed
EP-0979103-A1 COMPOUNDS NYCOMED IMAGING AS (NO) 2000-02-16 EP disclosed
WO-1998048838-A1 COMPOUNDS NYCOMED IMAGING AS (NO) 1998-11-05 WO disclosed
US-4155913-A ANTICONBULSANTS, MUSCLE RELAXANTS AND SEDATIVES HOFFMANN-LA ROCHE INC. (US) 1979-05-22 US disclosed