Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876289 | 0.94 | CCR3 (0.51) | CCR3CYP2D6 | |
| SCHEMBL4606343 | 0.93 | CCR3 (0.48) | CCR3CYP2D6 | |
| SCHEMBL4606115 | 0.92 | CCR3 (0.48) | CCR3CYP2D6 | |
| SCHEMBL4603428 | 0.89 | CCR3 (0.47) | CCR3CYP2D6 | |
| SCHEMBL4605678 | 0.87 | CCR3 (0.45) | CCR3CYP2D6 | |
| SCHEMBL4604788 | 0.86 | CCR3 (0.60) | CCR3CYP2D6 | |
| SCHEMBL4605178 | 0.85 | CCR3 (0.47) | CCR3CYP2D6 | |
| SCHEMBL4604471 | 0.85 | CCR3 (0.57) | CCR3CYP2D6 | |
| SCHEMBL4603378 | 0.84 | CCR3 (0.47) | CCR3CYP2D6 | |
| SCHEMBL4604462 | 0.84 | CCR3 (0.55) | CCR3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943235-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Novartis AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | disclosed |