SCHEMBL460573

SCHEMBL460573

O=[C]CCC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL834934 0.81
SCHEMBL835553 0.79
SCHEMBL834424 0.77
SCHEMBL605855 0.67
SCHEMBL16415107 0.67
SCHEMBL269536 0.67
SCHEMBL14658476 0.67
SCHEMBL14659001 0.67
SCHEMBL15352216 0.67
SCHEMBL1366180 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546235-B1 WATER-SOLUBLE POLYMER ALKANALS NEKTAR THERAPEUTICS (US) 2021-10-20 EP claimed
JP-4764630-B2 2011-09-07 JP claimed
CN-1329427-C Water soluble polymer alkanals NEKTAR THERAPEUTICS CORP (US) 2007-08-01 CN claimed
US-7157546-B2 Polyoxyethylene glycol; purity, storage stability NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-01-02 US claimed
US-20060194940-A1 2-methylbutyraldehyde diethyl acetal end capped polyoxyethylene glycol; polyalkylene oxide, polyivnylpyrrolidone, polyvinyl alcohol, polyoxazoline etc. endcapped with polyetherpolyamine copolymers or oligomers covalently attached to diacetal tetramethylene group NEKTAR THERAPEUTICS AL, CORPORATION (US) 2006-08-31 US claimed
JP-2005538224-A 2005-12-15 JP claimed
CN-1688631-A Water soluble polymer alkanals NEKTAR THERAPEUTICS AL CORP (US) 2005-10-26 CN claimed
EP-1546235-A2 WATER-SOLUBLE POLYMER ALKANALS Nektar Therapeutics Al, Corporation (US) 2005-06-29 EP claimed
US-20040116649-A1 Polyoxyethylene glycol; purity, storage stability NEKTAR THERAPEUTICS 2004-06-17 US claimed
WO-2004022630-A2 WATER-SOLUBLE POLYMER ALKANALS NEKTAR THERAPEUTICS AL, CORPORATION (US) 2004-03-18 WO claimed
US-5877321-A NEUROKININ RECEPTOR SANOFI (FR) 1999-03-02 US claimed
US-11541023-B2 Compounds and compositions for the treatment of neurodegenerative and inflammatory diseases SARBONNE UNIVERSITE (FR) 2023-01-03 US disclosed
CN-114728992-A Method for producing phosphate compound 斯泰拉化工公司 2022-07-08 CN disclosed
EP-1546235-B1 WATER-SOLUBLE POLYMER ALKANALS NEKTAR THERAPEUTICS (US) 2021-10-20 EP disclosed
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
EP-0045198-A2 1,1-Disubstituted carba-2-penems and their production Takeda Chemical Industries, Ltd. (JP) 1982-02-03 EP disclosed
US-4298606-A Thiazolylacetamido compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-11-03 US disclosed
US-4205180-A CHEMICAL INTERMEDIATES FOR NOVEL CEPHALOSPORIN COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-05-27 US disclosed
US-4203899-A Thiazolylacetamido compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1980-05-20 US disclosed
US-4098888-A THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-07-04 US disclosed