Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.84 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608046 | 1.00 | GRIA4 (0.84) | GRIA4GRIA2KCNH2 | |
| SCHEMBL6573061 | 0.92 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4606344 | 0.92 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4605907 | 0.92 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4608018 | 0.92 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL14141376 | 0.88 | GRIA4 (0.71) | GRIA4GRIA2KCNH2 | |
| SCHEMBL14141330 | 0.88 | GRIA4 (0.71) | GRIA4GRIA2KCNH2 | |
| SCHEMBL14141325 | 0.88 | GRIA4 (0.71) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607603 | 0.87 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4604922 | 0.87 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |