Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | PRKX | P51817 | 1/20 | 0.52 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827185 | 0.85 | KDM4E (0.50) | MRGPRX4S1PR1F10POLBKDM4E | |
| SCHEMBL1827641 | 0.84 | KDM4E (0.51) | RXFP1F10KDM4EHSD17B10 | |
| SCHEMBL1825725 | 0.83 | KDM4E (0.47) | MRGPRX4RXFP1F10POLBKDM4E | |
| SCHEMBL1825233 | 0.83 | KDR (0.49) | F10KDM4EHSD17B10 | |
| SCHEMBL1826827 | 0.83 | KDM4E (0.50) | S1PR1S1PR5RXFP1FFAR1PRKX | |
| SCHEMBL1824147 | 0.83 | KDM4E (0.47) | MRGPRX4FFAR1F10KDM4EHSD17B10 | |
| SCHEMBL1822714 | 0.82 | KDM4E (0.49) | MRGPRX4S1PR1S1PR5PDGFRAF10 | |
| SCHEMBL1825932 | 0.82 | S1PR1 (0.50) | S1PR1KDM4EHSD17B10 | |
| SCHEMBL1824122 | 0.82 | KDM4E (0.49) | RXFP1F10KDM4EHSD17B10 | |
| SCHEMBL1826416 | 0.82 | MRGPRX4 (0.50) | MRGPRX4S1PR1F10KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914152-B | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB | 2010-06-09 | — | — | CN | disclosed |
| EP-1720825-B1 | ANTHRANILIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USE AS DHODH INHIBITORS | ACTIVE BIOTECH AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| CN-1914152-A | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2007-02-14 | — | — | CN | disclosed |
| EP-1720825-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | Active Biotech AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| US-7074831-B2 | Compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2006-07-11 | — | — | US | disclosed |
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2005-08-25 | — | — | US | disclosed |
| WO-2005075410-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | MALT1, TPMT, FUCA1 | NR4A2 1796/4885MRGPRX4 420/4885MAPT 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.