Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.68 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.55 |
| ▸ | PREP | P48147 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665998 | 1.00 | DPP4 (0.68) | DPP4DPP8DPP7PREP | |
| SCHEMBL4604399 | 0.94 | DPP4 (0.67) | DPP4DPP8DPP7PREP | |
| SCHEMBL666252 | 0.94 | DPP4 (0.67) | DPP4DPP8DPP7PREP | |
| SCHEMBL4669433 | 0.83 | DPP4 (0.67) | DPP4DPP8DPP7PREP | |
| SCHEMBL665953 | 0.83 | DPP4 (0.67) | DPP4DPP8DPP7PREP | |
| SCHEMBL1437709 | 0.79 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL665486 | 0.79 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL4604380 | 0.75 | DPP4 (0.62) | DPP4DPP8DPP7PREP | |
| SCHEMBL663966 | 0.75 | DPP4 (0.62) | DPP4DPP8DPP7PREP | |
| SCHEMBL4594039 | 0.75 | DPP4 (0.74) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917001-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007017423-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-15 | — | — | WO | disclosed |