Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.64 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607203 | 1.00 | GRIA4 (0.64) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607245 | 0.89 | GRIA4 (0.60) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4606151 | 0.89 | GRIA4 (0.60) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607959 | 0.89 | GRIA4 (0.60) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4606366 | 0.89 | GRIA4 (0.60) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607852 | 0.86 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL14141449 | 0.85 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607603 | 0.85 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4604922 | 0.85 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4608046 | 0.84 | GRIA4 (0.84) | GRIA4GRIA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |