Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CD81 | P60033 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029241 | 0.91 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6710670 | 0.88 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8382803 | 0.88 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6266348 | 0.86 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3793027 | 0.86 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8009298 | 0.86 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28544460 | 0.83 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29897613 | 0.83 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28106680 | 0.83 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acetic Acid SCHEMBL11743292 | 0.82 | TSHR (0.83) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036103-B2 | MODIFIED POLYURETHANE HOTMELT ADHESIVE | HENKEL AG & CO KGAA (DE) | 2008-07-16 | — | — | EP | claimed |
| EP-1036103-B1 | MODIFIED POLYURETHANE HOTMELT ADHESIVE | HENKEL KGAA (DE) | 2002-09-11 | — | — | EP | claimed |
| JP-2001525429-A | — | — | 2001-12-11 | — | — | JP | claimed |
| EP-1036103-A1 | MODIFIED POLYURETHANE HOTMELT ADHESIVE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-09-20 | — | — | EP | claimed |
| WO-1999028363-A1 | MODIFIED POLYURETHANE HOTMELT ADHESIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-06-10 | — | — | WO | claimed |