Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 17/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.64 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.52 |
| ▸ | CALCA | P06881 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144584 | 0.91 | CALCRL (0.53) | CALCRLCYP3A4RAMP1CALCA | |
| SCHEMBL2026964 | 0.91 | CALCRL (0.53) | CALCRLCYP3A4RAMP1CALCA | |
| SCHEMBL3903201 | 0.85 | CALCRL (0.60) | CALCRLCYP3A4RAMP1CALCA | |
| SCHEMBL2031664 | 0.84 | CALCRL (0.46) | CALCRLCYP3A4RAMP1CALCA | |
| SCHEMBL3900985 | 0.84 | CALCRL (0.47) | CALCRLCYP3A4RAMP1CALCA | |
| SCHEMBL3277961 | 0.82 | CALCRL (0.53) | CALCRLCYP3A4 | |
| SCHEMBL3279641 | 0.81 | CALCRL (0.53) | CALCRLCYP3A4CALCA | |
| SCHEMBL4150835 | 0.81 | CALCRL (0.75) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL13313769 | 0.81 | CALCRL (0.53) | CALCRLCYP3A4RAMP1CALCA | |
| SCHEMBL13313782 | 0.81 | CALCRL (0.46) | CALCRLCYP3A4RAMP1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | claimed |
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |