Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.64 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14141258 | 1.00 | GRIA4 (0.64) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4605422 | 1.00 | GRIA4 (0.64) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4606570 | 1.00 | GRIA4 (0.64) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4606949 | 0.90 | GRIA4 (0.60) | GRIA4GRIA2 | |
| SCHEMBL4606558 | 0.90 | GRIA4 (0.60) | GRIA4GRIA2 | |
| SCHEMBL4607603 | 0.88 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4604922 | 0.88 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL14141449 | 0.88 | GRIA4 (0.68) | GRIA4GRIA2KCNH2 | |
| SCHEMBL3195715 | 0.84 | GRIA2 (0.56) | GRIA4GRIA2KCNH2 | |
| SCHEMBL13484271 | 0.84 | GRIA4 (0.45) | GRIA4GRIA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | claimed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | claimed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |