Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457829 | 0.91 | ADORA2A (0.54) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL2201752 | 0.91 | TP53 (0.50) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL29809280 | 0.90 | ADORA2A (0.55) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL567355 | 0.90 | ADORA2A (0.55) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL29353173 | 0.88 | TP53 (0.57) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL11458579 | 0.88 | TP53 (0.57) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL2198652 | 0.88 | TP53 (0.52) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL2198603 | 0.87 | TP53 (0.49) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL14415240 | 0.87 | TP53 (0.49) | TP53CYP2C9NFKB1MAPK1HSD17B10 | |
| SCHEMBL2198921 | 0.87 | ADORA2A (0.61) | TP53CYP2C9NFKB1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011606-A1 | PROCESS FOR PREPARING ADENINE COMPOUNDS AND INTERMEDIATES THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-01-26 | — | — | WO | disclosed |