Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.93 |
| ▸ | LMNA | P02545 | 1/20 | 0.93 |
| ▸ | HPGD | P15428 | 1/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.93 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.93 |
| ▸ | ENO1 | P06733 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
| ▸ | PGK2 | P07205 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfonet SCHEMBL10490966 | 1.00 | MEN1 (0.93) | MEN1LMNAHPGDTSHRBLM | |
| Fosfonet SCHEMBL15612 | 0.97 | — | — | |
| Fosfonet SCHEMBL26676054 | 0.93 | — | — | |
| Fosfonet SCHEMBL2801407 | 0.93 | — | — | |
| Fosfonet SCHEMBL26676053 | 0.93 | MEN1 (0.93) | MEN1LMNAHPGDTSHRBLM | |
| Fosfonet SCHEMBL11026013 | 0.93 | — | — | |
| Fosfonet SCHEMBL9162319 | 0.93 | — | — | |
| Fosfonet SCHEMBL15510455 | 0.93 | MEN1 (0.93) | MEN1LMNAHPGDTSHRBLM | |
| Fosfonet SCHEMBL28151124 | 0.93 | — | — | |
| Fosfonet SCHEMBL5521510 | 0.90 | MEN1 (0.88) | MEN1LMNAHPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806532-A | ADMINISTERING PHOSPHONOFORMIC AND PHOSPHONOACETIC ACID AND SALTS; GLANDULAR DISORDERS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1989-02-21 | — | — | US | claimed |
| EP-0652772-B2 | HERPESVIRUS VACCINES | HARVARD COLLEGE (US) | 2008-07-23 | — | — | EP | disclosed |
| US-7223411-B1 | Herpesvirus replication defective mutants | DANA-FARBER CANCER INSTITUTE (US) | 2007-05-29 | — | — | US | disclosed |
| EP-0739414-B1 | HERPESVIRUS REPLICATION DEFECTIVE MUTANTS | HARVARD COLLEGE (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-0652772-B1 | HERPESVIRUS VACCINES | HARVARD COLLEGE (US) | 2002-11-20 | — | — | EP | disclosed |
| US-20020086035-A1 | HERPEVIRUS REPLICATION DEFECTIVE MUTANTS | DANA-FARBER CANCER INSTITUTE | 2002-07-04 | — | — | US | disclosed |
| US-20020009462-A1 | HERPESVIRUS REPLICATION DEFECTIVE MUTANTS | DANA-FARBER CANCER INSTITUTE | 2002-01-24 | — | — | US | disclosed |
| WO-1999006069-A1 | HERPES VIRUS REPLICATION DEFECTIVE MUTANTS | DANA FARBER CANCER INSTITUTE (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0739414-A1 | HERPESVIRUS REPLICATION DEFECTIVE MUTANTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0652772-A4 | HERPESVIRUS VACCINES. | HARVARD COLLEGE (US) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995018852-A1 | HERPESVIRUS REPLICATION DEFECTIVE MUTANTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1995-07-13 | — | — | WO | disclosed |
| EP-0652772-A1 | HERPESVIRUS VACCINES | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003207-A1 | HERPESVIRUS VACCINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0043141-B1 | PHARMACEUTICAL COMPOSITIONS HAVING ANTIVIRAL ACTIVITY FOR TOPICAL ADMINISTRATION AND THE USE OF 1-(SUBSTITUTED PHENYL)-5-(4-MORPHOLINYL)-1-PENTEN-3-ONE COMPOUNDS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS HAVING AN ANTIVIRAL EFFECT | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-09-12 | — | — | EP | disclosed |
| US-4400380-A | HERBES VIRUS; TOPICAL | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0043141-A1 | Pharmaceutical compositions having antiviral activity for topical administration and the use of 1-(substituted phenyl)-5-(4-morpholinyl)-1-penten-3-one compounds for the preparation of pharmaceutical compositions having an antiviral effect | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-01-06 | — | — | EP | disclosed |