Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606519 | 1.00 | KDM1A (0.47) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL28817269 | 1.00 | KDM1A (0.47) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL19297438 | 0.96 | KDM1A (0.47) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL19297536 | 0.96 | KDM1A (0.47) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL8724940 | 0.96 | KDM1A (0.47) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL21838934 | 0.87 | KDM1A (0.56) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL14804306 | 0.80 | KDM1A (0.56) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL26318046 | 0.80 | KDM1A (0.56) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL25341890 | 0.79 | SLC18A3 (0.49) | GRIA4HTR2CHTR2BAR | |
| SCHEMBL8326083 | 0.79 | KDM1A (0.47) | KDM1AHTR2CHTR2BHRH3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |