Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.63 |
| ▸ | CCR1 | P32246 | 9/20 | 0.49 |
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937982 | 0.85 | PTGDR2 (0.70) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL1714226 | 0.83 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1713552 | 0.80 | PTGDR2 (0.78) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL27748339 | 0.80 | PTGDR2 (0.78) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL5060610 | 0.80 | CCR1 (0.66) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL1714755 | 0.80 | PTGDR2 (0.80) | PTGDR2 | |
| SCHEMBL4942133 | 0.79 | PTGDR2 (0.78) | PTGDR2 | |
| SCHEMBL27693218 | 0.78 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1713638 | 0.77 | PTGDR2 (1.00) | PTGDR2CCR1FPR3GPR65GPR35 | |
| SCHEMBL6246835 | 0.77 | CCR1 (0.67) | PTGDR2CCR1FPR3GPR65GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948630-A2 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007052023-A2 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-05-10 | — | — | WO | disclosed |