Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | OGA | O60502 | 5/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16048417 | 0.80 | HDAC3 (0.58) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4814736 | 0.80 | HDAC3 (0.73) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2575502 | 0.80 | HRH3 (0.58) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3159765 | 0.78 | HRH3 (0.54) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20176409 | 0.76 | HRH3 (0.57) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4818519 | 0.76 | HRH3 (0.50) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14844122 | 0.75 | HRH3 (1.00) | HRH3 | |
| SCHEMBL4813646 | 0.75 | HRH3 (0.49) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4624452 | 0.75 | HRH3 (0.52) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4807896 | 0.74 | HDAC3 (0.74) | HRH3HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |