Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818191 | 1.00 | ANPEP (0.43) | ANPEPERAP1ERAP2TAAR1MEN1 | |
| SCHEMBL3670997 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL5732556 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL4912039 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL1683190 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL6562522 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL1817802 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL3870627 | 0.81 | EPHX1 (0.50) | ANPEPTAAR1CYP2A6EPHX1SLC6A2 | |
| SCHEMBL3134409 | 0.80 | ANPEP (0.42) | ANPEPERAP1ERAP2TAAR1CYP2A6 | |
| SCHEMBL11246640 | 0.78 | KDM4E (0.45) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948243-A2 | POLYCATION-POLYANION COMPLEXES, COMPOSITIONS AND METHODS OF USE THEREOF | Aeris Therapeutics, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007055950-A2 | POLYCATION-POLYANION COMPLEXES, COMPOSITIONS AND METHODS OF USE THEREOF | AERIS THERAPEUTICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |