Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610044 | 0.91 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL4608678 | 0.90 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL4608680 | 0.90 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL4609265 | 0.89 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL4607736 | 0.89 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL4607737 | 0.89 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL4608706 | 0.88 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL4608701 | 0.88 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL4608455 | 0.87 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL4609855 | 0.87 | MAPK14 (0.59) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747204-B1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | PROCTER & GAMBLE (US) | 2008-07-30 | — | — | EP | disclosed |
| CN-1946701-A | Trisubstituted ureas as cytokine inhibitors | PROCTER & GAMBLE (US) | 2007-04-11 | — | — | CN | disclosed |