Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 9/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609449 | 0.90 | TACR2 (0.55) | TACR2TACR1MCHR1 | |
| SCHEMBL4611535 | 0.89 | TACR2 (0.53) | TACR2TACR1 | |
| SCHEMBL4609381 | 0.84 | TACR2 (0.75) | TACR2TACR1 | |
| SCHEMBL14434385 | 0.84 | TACR2 (0.75) | TACR2TACR1 | |
| SCHEMBL4609840 | 0.82 | TACR2 (0.50) | TACR2TACR1 | |
| SCHEMBL14434394 | 0.76 | TACR2 (0.51) | TACR2TACR1MCHR1 | |
| SCHEMBL4609755 | 0.76 | MCHR1 (0.46) | TACR2TACR1MCHR1 | |
| SCHEMBL14435100 | 0.74 | TACR2 (0.77) | TACR2TACR1 | |
| SCHEMBL4609451 | 0.74 | TACR2 (0.77) | TACR2TACR1 | |
| SCHEMBL8828884 | 0.74 | TACR2 (0.69) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979319-A1 | NOVEL DUAL NK2/NK3-ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESSES FOR THEIR PREPARATIONS | Solvay Pharmaceuticals GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088181-A1 | NOVEL DUAL NK2/NK3-ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESSES FOR THEIR PREPARATIONS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |