Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295490 | 0.94 | PTGER4 (1.00) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL10058592 | 0.91 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL1590327 | 0.89 | PTGER4 (0.86) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL2432521 | 0.88 | PTGER4 (0.88) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL2429985 | 0.88 | PTGER4 (0.88) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3227301 | 0.88 | PTGER4 (0.88) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3227318 | 0.88 | PTGER4 (0.88) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL12002071 | 0.87 | PTGER4 (0.81) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL1590297 | 0.87 | PTGER4 (0.86) | PTGER4 | |
| SCHEMBL2298754 | 0.86 | PTGER4 (0.86) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979317-B1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-8207213-B2 | Benzoisoindole derivatives for the treatment of pain | GLAXO GROUP LIMITED (GB) | 2012-06-26 | — | — | US | disclosed |
| EP-1979317-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088189-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | WO | disclosed |