Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459411 | 0.94 | MAPT (0.41) | MAPTKLK7KLK5L3MBTL1POLB | |
| SCHEMBL458953 | 0.84 | CCNE2 (0.36) | MAPTL3MBTL1POLBMAPK1SYK | |
| SCHEMBL460716 | 0.82 | MAPT (0.36) | MAPTKLK7KLK5L3MBTL1POLB | |
| SCHEMBL459081 | 0.76 | MAPT (0.37) | MAPTKLK7KLK5L3MBTL1POLB | |
| SCHEMBL458787 | 0.76 | CCNE2 (0.36) | MAPTMAPK1SYKTDP1CCNE2 | |
| SCHEMBL10077228 | 0.74 | SYK (0.36) | MAPTL3MBTL1POLBMAPK1SYK | |
| SCHEMBL3669146 | 0.73 | RXFP1 (0.34) | MAPTL3MBTL1SYKCCNE2CCNE1 | |
| SCHEMBL459649 | 0.72 | CCNE2 (0.34) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL459585 | 0.72 | CCNA2 (0.39) | MAPTKLK5MAPK1SYKCCNE2 | |
| SCHEMBL432254 | 0.69 | CCNE2 (0.40) | MAPTBRD4CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596102-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GeneArrest Ltd (IL) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011114-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENEARREST LTD (IL) | 2012-01-26 | — | — | WO | disclosed |