⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462081 | 0.74 | — | — | |
| SCHEMBL13359345 | 0.70 | — | — | |
| Hydantoin SCHEMBL9391323 | 0.69 | — | — | |
| SCHEMBL6166624 | 0.67 | — | — | |
| SCHEMBL84315 | 0.67 | — | — | |
| SCHEMBL27322173 | 0.67 | — | — | |
| SCHEMBL4525780 | 0.67 | — | — | |
| SCHEMBL27522623 | 0.67 | — | — | |
| Thiohydantoin SCHEMBL17153849 | 0.67 | — | — | |
| SCHEMBL27335105 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-1371646-B1 | ARYL-SUBSTITUTED ALICYCLIC COMPOUND AND MEDICAL COMPOSITION COMPRISING THE SAME | DAINIPPON SUMITOMO PHARMA CO (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-7659263-B2 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20090036444-A1 | 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1948635-A1 | BENZIMIDAZOLE DERIVATIVES AS GYRASE INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007056330-A1 | BENZIMIDAZOLE DERIVATIVES AS GYRASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-05-18 | — | — | WO | disclosed |
| EP-1473330-B1 | Process for the synthesis of oxonol compound | FUJI PHOTO FILM CO LTD (JP) | 2007-02-14 | — | — | EP | disclosed |
| US-4923504-A | 2-(2-Imidazolin-2-yl)pyridines and quinolines, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4638068-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-01-20 | — | — | US | disclosed |