Biphenyl

Biphenyl

SCHEMBL4609545

CC(C)c1cccc2sc3ccccc3c(=O)c12.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 4/20 0.43
POLB P06746 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
GAA P10253 2/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
KDM4E B2RXH2 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MAPK1 P28482 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29675381 0.94 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL27760689 0.94 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL29359906 0.94 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL52045 0.94 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL25183175 0.92 MAPT (0.49) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL30478400 0.92 MAPT (0.49) MAPTNPC1RAB9ACYP1A2CYP3A4
Iodide SCHEMBL31364215 0.92 MAPT (0.49) MAPTNPC1RAB9ACYP1A2CYP3A4
Acetone SCHEMBL1615361 0.88 MAPT (0.46) MAPTNPC1RAB9ACYP1A2CYP3A4
Anthraquinone SCHEMBL28000312 0.88 MAPT (0.46) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL31129122 0.87 MAPT (0.43) MAPTNPC1RAB9ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080286486-A1 Carbonate Containing Energy-Curable Compositions SUN CHEMICAL CORP. (US) 2008-11-20 US disclosed
US-20080268169-A1 Cationically Curable Coating Compositions SUN CHEMICAL CORPORATION (US) 2008-10-30 US disclosed
EP-1948711-A1 CYCLOCARBONATE-CONTAINING ENERGY-CURABLE COMPOSITIONS Sun Chemical Corporation (US) 2008-07-30 EP disclosed
EP-1817360-A2 CATIONICALLY CURABLE COATING COMPOSITIONS Sun Chemical Limited (GB) 2007-08-15 EP disclosed
WO-2007055929-A1 CYCLOCARBONATE-CONTAINING ENERGY-CURABLE COMPOSITIONS SUN CHEMICAL CORPORATION (US) 2007-05-18 WO disclosed
WO-2006060281-A2 CATIONICALLY CURABLE COATING COMPOSITIONS SUN CHEMICAL LIMITED (GB) 2006-06-08 WO disclosed