Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611034 | 0.85 | IGF1R (0.58) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL31330458 | 0.83 | IGF1R (0.71) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL1879763 | 0.83 | IGF1R (0.71) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL1879449 | 0.83 | IGF1R (0.63) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL4882133 | 0.82 | IGF1R (0.62) | IGF1RPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL1880633 | 0.82 | IGF1R (0.70) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL14465230 | 0.82 | IGF1R (0.57) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL1879790 | 0.81 | IGF1R (0.71) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL12636477 | 0.80 | IGF1R (0.67) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL4152463 | 0.80 | IGF1R (0.64) | IGF1RPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979339-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007083017-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2007-07-26 | — | — | WO | disclosed |