SCHEMBL4610326

SCHEMBL4610326

C=CCCCC[Si](C)(C)CCCCCCCC

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.70
ALDH1A1 P00352 2/20 0.54
FAAH O00519 3/20 0.36
TRPV1 Q8NER1 1/20 0.35
THRB P10828 1/20 0.35
ABCC4 O15439 1/20 0.34
MAPT P10636 1/20 0.34
TOP1 P11387 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29236761 0.91 TSHR (0.52) TSHRALDH1A1ABCC4MAPT
SCHEMBL30890195 0.91 TSHR (0.52) TSHRALDH1A1ABCC4MAPT
SCHEMBL29236617 0.91 TSHR (0.52) TSHRALDH1A1ABCC4MAPT
SCHEMBL1241800 0.89 TSHR (0.48) TSHRALDH1A1ABCC4MAPT
SCHEMBL10843200 0.87 TSHR (0.70) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL10842911 0.87 TSHR (0.70) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL10842401 0.87 TSHR (0.70) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL10843332 0.87 TSHR (0.70) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL10841703 0.87 TSHR (0.70) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL10841407 0.84 TSHR (0.73) TSHRALDH1A1FAAHTRPV1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1018535-B1 Solvent-free vinyl acetate-ethylene compositions comprising an acrylic polymer CELANESE INT CORP (US) 2005-12-07 EP claimed
US-6541566-B1 Provides increased shear strength without decreased loop tack; may be applied to paper without bleeding through NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-04-01 US claimed
EP-1018522-A1 Coating compositions prepared with a sterically hindered alkoxylated silane National Starch and Chemical Investment Holding Corporation (US) 2000-07-12 EP claimed
EP-1018535-A1 Solvent-free vinyl acetate-ethylene compositions comprising an acrylic polymer National Starch and Chemical Investment Holding Corporation (US) 2000-07-12 EP claimed
EP-1219650-B1 Star polymer colloidal stabilizers NAT STARCH CHEM INVEST (US) 2008-10-08 EP disclosed
EP-1018535-B1 Solvent-free vinyl acetate-ethylene compositions comprising an acrylic polymer CELANESE INT CORP (US) 2005-12-07 EP disclosed
US-6541566-B1 Provides increased shear strength without decreased loop tack; may be applied to paper without bleeding through NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-04-01 US disclosed
EP-1219650-A2 Star polymer colloidal stabilizers National Starch and Chemical Investment Holding Corporation (US) 2002-07-03 EP disclosed
EP-1018535-A1 Solvent-free vinyl acetate-ethylene compositions comprising an acrylic polymer National Starch and Chemical Investment Holding Corporation (US) 2000-07-12 EP disclosed
EP-1018522-A1 Coating compositions prepared with a sterically hindered alkoxylated silane National Starch and Chemical Investment Holding Corporation (US) 2000-07-12 EP disclosed