Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561041 | 0.94 | PTGER4 (0.82) | PTGER4CYP1A2CYP2D6PPARG | |
| SCHEMBL3566760 | 0.91 | PTGER4 (0.89) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL4410607 | 0.91 | PTGER4 (0.89) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3573521 | 0.90 | PTGER4 (0.83) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL11967638 | 0.89 | PTGER4 (0.74) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL4620056 | 0.89 | PTGER4 (0.74) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3571086 | 0.89 | PTGER4 (0.80) | PTGER4CYP1A2CYP2D6PPARG | |
| SCHEMBL27740580 | 0.89 | PTGER4 (0.61) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3568198 | 0.88 | PTGER4 (0.71) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3565993 | 0.87 | PTGER4 (0.77) | PTGER4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979317-B1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| EP-1979317-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088189-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | WO | disclosed |