Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611322 | 1.00 | CYP2D6 (0.61) | CYP2D6HKDC1KMT2ALMNAHSD17B10 | |
| SCHEMBL4612061 | 1.00 | CYP2D6 (0.61) | CYP2D6HKDC1KMT2ALMNAHSD17B10 | |
| SCHEMBL3395163 | 1.00 | CYP2D6 (0.61) | CYP2D6HKDC1KMT2ALMNAHSD17B10 | |
| SCHEMBL4612358 | 1.00 | CYP2D6 (0.61) | CYP2D6HKDC1KMT2ALMNAHSD17B10 | |
| SCHEMBL3497342 | 0.90 | CYP2D6 (0.50) | CYP2D6HKDC1KMT2APOLBMEN1 | |
| SCHEMBL7527118 | 0.85 | TDP1 (0.52) | CYP2D6HKDC1KMT2ALMNAHSD17B10 | |
| SCHEMBL29175552 | 0.82 | CYP2D6 (0.59) | CYP2D6HKDC1KMT2ALMNAHSD17B10 | |
| SCHEMBL67127 | 0.82 | CYP2D6 (0.64) | CYP2D6KMT2ALMNAHSD17B10SRC | |
| SCHEMBL16093072 | 0.82 | CYP2D6 (0.64) | CYP2D6KMT2ALMNASRCMAPK1 | |
| SCHEMBL10441680 | 0.82 | PDPK1 (0.53) | CYP2D6HKDC1KMT2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1621546-B1 | Peptide ligands specific to immonoglobulins | TECNOGEN SPA (IT) | 2008-10-29 | — | — | EP | claimed |