⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332954 | 0.82 | — | — | |
| SCHEMBL20484614 | 0.82 | GABRR1 (0.41) | — | |
| SCHEMBL28814682 | 0.79 | GABRR1 (0.39) | — | |
| SCHEMBL28204122 | 0.79 | GABRR1 (0.39) | — | |
| SCHEMBL27987510 | 0.79 | GABRR1 (0.39) | — | |
| SCHEMBL15871152 | 0.79 | GABRR1 (0.39) | — | |
| SCHEMBL7105689 | 0.79 | GABRR1 (0.39) | — | |
| SCHEMBL27987515 | 0.79 | GABRR1 (0.39) | — | |
| SCHEMBL16731995 | 0.77 | — | — | |
| SCHEMBL1039605 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678665-B | Organic silicon compound containing cyclodextrin group | WACKER CHEMIE GMBH | 2011-06-15 | — | — | CN | disclosed |
| CN-102070903-A | Organosilicon compounds comprising cyclodextrin radicals | WACKER CHEMIE GMBH | 2011-05-25 | — | — | CN | disclosed |
| EP-1865016-B1 | Organosilicon compounds comprising cyclodextrin radicals | WACKER CHEMIE AG (DE) | 2008-11-26 | — | — | EP | disclosed |
| EP-1530607-B1 | ORGANOSILICON COMPOUNDS COMPRISING CYCLODEXTRIN RADICALS | WACKER CHEMIE AG (DE) | 2008-10-29 | — | — | EP | disclosed |
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| EP-1865016-A1 | Organosilicon compounds comprising cyclodextrin radicals | Wacker Chemie AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| US-20060009592-A1 | Organosilicon compounds comprising cyclodextrin radicals | WACKER-CHEMIE GMBH (DE) | 2006-01-12 | — | — | US | disclosed |
| CN-1678665-A | Organic silicon compound containing cyclodextrin group | WACKER CHEMIE GMBH (DE) | 2005-10-05 | — | — | CN | disclosed |
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5306816-A | Processes for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0499196-A1 | Intermediates and process for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |