Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612805 | 1.00 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL26290907 | 1.00 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5806797 | 0.83 | HCAR2 (0.43) | TSHRHCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL6439242 | 0.83 | HCAR2 (0.43) | TSHRHCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL5806800 | 0.83 | HCAR2 (0.43) | TSHRHCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL11125039 | 0.80 | MGAM (0.35) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8104032 | 0.78 | MGAM (0.34) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL6732240 | 0.78 | MGAM (0.34) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8226112 | 0.78 | MGAM (0.34) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL996820 | 0.78 | MGAM (0.34) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615871-B1 | PROCESS FOR THE PREPARATION OF DIALKYL 3-OXOGLUTARATES | EGIS GYOGYSZERGYAR NYILVANOSAN (HU) | 2008-10-29 | — | — | EP | disclosed |
| EP-1615871-A2 | PROCESS FOR THE PREPARATION OF DIALKYL 3-OXOGLUTARATES | EGIS GYOGYSZERGYAR RT. (HU) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089867-A2 | PROCESS FOR THE PREPARATION OF DIALKYL 3-OXOGLUTARATES | EGIS Gyógyszergyár Rt. (HU) | 2004-10-21 | — | — | WO | disclosed |