⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435438 | 0.81 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL30851 | 0.81 | — | — | |
| SCHEMBL6435439 | 0.81 | SMN1; SMN2 (0.52) | — | |
| Methane SCHEMBL27388128 | 0.79 | — | — | |
| Charcoal, Activated SCHEMBL890031 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL1076016 | 0.79 | — | — | |
| SCHEMBL9289678 | 0.77 | — | — | |
| SCHEMBL206600 | 0.77 | — | — | |
| SCHEMBL11289910 | 0.77 | — | — | |
| SCHEMBL1076380 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910292-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | claimed |
| US-20070149570-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | claimed |
| WO-2007015588-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-08 | — | — | WO | claimed |
| EP-1022949-A1 | SYNERGISTIC COMPOSITIONS COMPRISING AN OXATHIAZINE AND A BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDE | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-08-02 | — | — | EP | claimed |
| WO-1999018795-A1 | SYNERGISTIC COMPOSITIONS COMPRISING AN OXATHIAZINE AND A BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDE | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-04-22 | — | — | WO | claimed |
| EP-0699193-A1 | CARBOXYLIC ACID AMIDE BENZOTHIOPHENE-S-OXIDES | BAYER AG (DE) | 1996-03-06 | — | — | EP | claimed |
| EP-0512349-B1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1996-02-14 | — | — | EP | claimed |
| WO-1994027986-A1 | CARBOXYLIC ACID AMIDE BENZOTHIOPHENE-S-OXIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | claimed |
| US-5244893-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | claimed |
| EP-0512349-A1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1992-11-11 | — | — | EP | claimed |
| EP-1910292-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20070149570-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| WO-2007015588-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-08 | — | — | WO | disclosed |
| WO-2006130627-A2 | METHODS FOR TREATING HEPATITIS C | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| US-5712304-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-27 | — | — | US | disclosed |
| EP-0699193-A1 | CARBOXYLIC ACID AMIDE BENZOTHIOPHENE-S-OXIDES | BAYER AG (DE) | 1996-03-06 | — | — | EP | disclosed |
| EP-0512349-B1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994027986-A1 | CARBOXYLIC ACID AMIDE BENZOTHIOPHENE-S-OXIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |
| US-5244893-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | disclosed |
| EP-0512349-A1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |