Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | MVD | P53602 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24701563 | 1.00 | ACE (0.54) | ACEABCC4MAPTRAB9AREN | |
| SCHEMBL6562015 | 1.00 | ACE (0.54) | ACEABCC4MAPTRAB9AREN | |
| SCHEMBL4478131 | 1.00 | ACE (0.54) | ACEABCC4MAPTRAB9AREN | |
| SCHEMBL14586443 | 0.88 | ACE (0.59) | ACERAB9ARENMVDCHRM2 | |
| SCHEMBL10005864 | 0.88 | ACE (0.59) | ACERAB9ARENMVDCHRM2 | |
| SCHEMBL10005860 | 0.88 | ACE (0.59) | ACERAB9ARENMVDCHRM2 | |
| SCHEMBL7298458 | 0.88 | ACE (0.66) | ACERENMVDCHRM2CHRM4 | |
| SCHEMBL6789458 | 0.88 | ACE (0.66) | ACERENMVDCHRM2CHRM4 | |
| SCHEMBL6784027 | 0.88 | ACE (0.66) | ACERENMVDCHRM2CHRM4 | |
| SCHEMBL6789464 | 0.88 | ACE (0.66) | ACERENMVDCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471881-B1 | USE OF A COMPOUND INACTIVATING THE KINASE A PROTEIN IN A COMPOSITION CONTAINING A COSMETICALLY ACCEPTABLE MEDIUM IN ORDER TO LIGHTEN THE SKIN | SEPPIC SA (FR) | 2008-10-15 | — | — | EP | disclosed |