SCHEMBL4613099

SCHEMBL4613099

CC(=O)C1C=CC(C(C)=O)C1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4613089 1.00 POLB (0.32) POLBAPEX1TDP1
SCHEMBL1786518 0.84
SCHEMBL15215794 0.82
SCHEMBL27546517 0.80 POLB (0.36) POLBTDP1
SCHEMBL13953760 0.78
SCHEMBL23809950 0.77
SCHEMBL1784820 0.73 ABAT (0.31)
SCHEMBL14944290 0.71 ABAT (0.31)
SCHEMBL12491781 0.71 POLB (0.42) POLBAPEX1TDP1
SCHEMBL1782951 0.71 POLB (0.31) POLBAPEX1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1428888-B1 Method for the production of (1S,4R)-(-)-4-Hydroxycyclopent-2-enyl esters ARCHIMICA GMBH (DE) 2008-10-22 EP claimed
US-6599754-B2 Semipermeable membrane separating the contents of the first chamber from the contents of the second chamber, wherein said semipermeable membrane is permeable to one or more products of a combinatorial library UNIVERSITY OF ROCHESTER 2003-07-29 US disclosed
EP-1311345-A1 BIPHASIC REACTION VESSEL AND METHODS OF USE University of Rochester (US) 2003-05-21 EP disclosed
US-20020085955-A1 Biphasic reaction vessel and methods of use ROCHESTER, UNIVERSITY OF 2002-07-04 US disclosed
WO-2001080998-A1 BIPHASIC REACTION VESSEL AND METHODS OF USE UNIVERSITY OF ROCHESTER (US) 2001-11-01 WO disclosed