Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613186 | 1.00 | PPARG (0.46) | PPARGNPC1LMNA | |
| SCHEMBL4614130 | 0.89 | PPARG (0.53) | PPARG | |
| SCHEMBL4614129 | 0.89 | PPARG (0.53) | PPARG | |
| SCHEMBL4616873 | 0.87 | PPARG (0.60) | PPARGNPC1 | |
| SCHEMBL4616876 | 0.87 | PPARG (0.60) | PPARGNPC1 | |
| SCHEMBL4527872 | 0.84 | PPARG (0.52) | PPARGLMNA | |
| SCHEMBL4527868 | 0.84 | PPARG (0.52) | PPARGLMNA | |
| SCHEMBL3202509 | 0.82 | PPARG (0.51) | PPARGNPC1LMNA | |
| SCHEMBL3202524 | 0.82 | PPARG (0.51) | PPARGNPC1LMNA | |
| SCHEMBL3217571 | 0.81 | PPARG (0.45) | PPARGNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |