SCHEMBL4613610

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4614032	0.82	CDK2 (0.80)	CDK2CDK4
	SCHEMBL4613643	0.80	CDK2 (0.50)	CDK2CDK4PLK1IKBKBABL1
	SCHEMBL2087002	0.79	CDK2 (0.72)	CDK2CDK4PLK1IKBKBALDH1A1
	SCHEMBL4615045	0.78	CDK2 (0.68)	CDK2CDK4
	SCHEMBL6605375	0.77	CDK2 (0.62)	CDK2CDK4PLK1IKBKBALDH1A1
	SCHEMBL6279175	0.74	CDK2 (0.61)	CDK2CDK4IKBKBALDH1A1ABL1
	SCHEMBL29369233	0.73	CDK2 (1.00)	CDK2CDK4PLK1ABL1AURKA
	SCHEMBL4798545	0.73	CDK2 (1.00)	CDK2CDK4PLK1ABL1AURKA
	SCHEMBL27664535	0.73	CDK2 (0.59)	CDK2CDK4PLK1IKBKBALDH1A1
	SCHEMBL2086429	0.73	CDK2 (0.69)	CDK2CDK4PLK1IKBKBABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.