SCHEMBL4613667

SCHEMBL4613667

Cc1c(C(=S)NC2CCCC(N)C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCCF)cc1.Cc1c(C(=S)Nc2ccc(C(F)(F)F)cn2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCCF)cc1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4247695 0.91 CNR1 (0.63) CNR1
SCHEMBL4247667 0.89 CNR1 (0.76) CNR1
SCHEMBL4245540 0.84 CNR1 (0.74) CNR1
SCHEMBL4242614 0.81 CNR1 (0.63) CNR1
SCHEMBL4245483 0.80 CNR1 (0.51) CNR1
SCHEMBL4612345 0.79 CNR1 (0.54) CNR1
SCHEMBL4252499 0.79 CNR1 (0.63) CNR1
SCHEMBL3090459 0.77 CNR1 (1.00) CNR1
SCHEMBL4253966 0.76 CNR1 (0.73) CNR1
SCHEMBL3090745 0.75 CNR1 (0.84) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910304-A2 THERAPEUTIC AGENTS AstraZeneca AB (SE) 2008-04-16 EP disclosed
WO-2007010222-A2 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2007-01-25 WO disclosed