SCHEMBL4614

SCHEMBL4614

Brc1ccnc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463643 1.00
Hydrochloric Acid SCHEMBL1258340 0.97
SCHEMBL833371 0.77 KDM4E (0.48)
SCHEMBL22912663 0.77 IDO1 (0.55)
SCHEMBL30362730 0.74 KDM4E (0.46)
SCHEMBL29806893 0.74
SCHEMBL146758 0.74
SCHEMBL132442 0.72
SCHEMBL179116 0.72
SCHEMBL526887 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111569806-A Catalytic reaction device for preparing 2, 4-dibromopyridine 上海巨启化学科技有限公司 2020-08-25 CN claimed
CN-106083837-B The preparation method of Yi Zhong oxazolidinones antibacterials and its intermediate 浙江普洛得邦制药有限公司 2018-08-31 CN claimed
CN-106083837-A A kind of oxazolidinone antibacterial medicine and the preparation method of intermediate thereof 浙江普洛得邦制药有限公司 2016-11-09 CN claimed
EP-0220080-B1 COMPOSITIONS BASED ON PHTHALONITRILE-TERMINATED POLYARYLOXY PYRIDINE OLIGOMERS, THEIR PREPARATION, THEIR USE IN THE PREPARATION OF POLYARYLOXY PYRIDINE COPHTHALOCYANINE LATTICES AND LATTICES OBTAINED CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1990-02-07 EP claimed
US-4764578-A Compositions of polyaryloxypyridine oligomers with phthalonitrile end groups, their preparation and use for manufacturing polyaryloxypyridine co-phthalocyanine lattices CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-08-16 US claimed
US-12637467-B2 Inhibitor of BTK and mutants thereof NEWAVE PHARMACEUTICAL INC. (US) 2026-05-26 US disclosed
WO-2026098632-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 江苏恒瑞医药股份有限公司 2026-05-15 WO disclosed
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
EP-3710428-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-25 EP disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
US-12516056-B2 Compounds for inhibition of janus kinase 1 MANKIND PHARMA LTD. (IN) 2026-01-06 US disclosed
WO-2002080926-A1 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS ABBOTT GMBH & CO. KG (DE) 2002-10-17 WO disclosed
EP-1212327-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-06-12 EP disclosed
WO-2001019829-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
US-6005112-A REACTING SUBSTITUTED OR UNSUBSTITUTED PYRIDINE METAL COMPOUND WITH SUBSTITUTED ISOCYANATE OR ISOTHIOCYANATE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-12-21 US disclosed
EP-0881217-A1 PROCESS FOR PRODUCING PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-02 EP disclosed
US-4814403-A CROSSLINKING-HEAT, OXIDATION RESISTANCE CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1989-03-21 US disclosed
US-4764578-A Compositions of polyaryloxypyridine oligomers with phthalonitrile end groups, their preparation and use for manufacturing polyaryloxypyridine co-phthalocyanine lattices CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-08-16 US disclosed
US-3974166-A FUNGICIDE CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed