SCHEMBL4614288

SCHEMBL4614288

Cc1c(C(=O)NC2CCCCC2O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.75
CNR2 P34972 13/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4896148 1.00 CNR1 (0.75) CNR1CNR2
SCHEMBL4902427 1.00 CNR1 (0.75) CNR1CNR2
SCHEMBL4900449 1.00 CNR1 (0.75) CNR1CNR2
SCHEMBL4898558 1.00 CNR1 (0.75) CNR1CNR2
SCHEMBL4906736 0.92 CNR1 (0.73) CNR1CNR2
SCHEMBL4904314 0.90 CNR1 (0.70) CNR1CNR2
SCHEMBL4893068 0.89 CNR1 (0.69) CNR1CNR2
SCHEMBL4893137 0.86 CNR1 (0.71) CNR1CNR2
SCHEMBL4615448 0.86 CNR1 (0.71) CNR1CNR2
SCHEMBL4615451 0.86 CNR1 (0.71) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940820-A1 MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS AstraZeneca AB (SE) 2008-07-09 EP disclosed
WO-2007031721-A1 MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS ASTRAZENECA AB (SE) 2007-03-22 WO disclosed