Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206833 | 0.89 | PPARG (0.54) | PPARGPOLBNPC1KDM4EALDH1A1 | |
| SCHEMBL4614505 | 0.89 | PPARG (0.52) | PPARGPOLBNPC1KDM4EALDH1A1 | |
| SCHEMBL3204500 | 0.83 | PPARG (0.58) | PPARGNPC1 | |
| SCHEMBL3208057 | 0.83 | PPARG (0.58) | PPARGNPC1 | |
| SCHEMBL3211081 | 0.82 | PPARG (0.53) | PPARG | |
| SCHEMBL3211063 | 0.82 | PPARG (0.53) | PPARG | |
| SCHEMBL4531217 | 0.81 | PPARG (0.54) | PPARGNPC1 | |
| SCHEMBL4531220 | 0.81 | PPARG (0.54) | PPARGNPC1 | |
| SCHEMBL3212888 | 0.81 | PPARG (0.55) | PPARGALDH1A1 | |
| SCHEMBL3212894 | 0.81 | PPARG (0.55) | PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |