Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613363 | 0.81 | NPC1 (0.39) | PPARGPDE2AFAAHDAOP2RX7 | |
| SCHEMBL3205336 | 0.78 | PPARG (0.57) | PPARGPDE2AFAAHKCNJ6KCNJ5 | |
| SCHEMBL3206847 | 0.77 | PPARG (0.49) | PPARGPDE2AFAAHKCNJ6KCNJ5 | |
| SCHEMBL4613928 | 0.76 | NPC1 (0.54) | PPARGFAAHKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL5120324 | 0.74 | PPARG (0.61) | PPARGPDE2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL3195607 | 0.72 | PPARG (0.66) | PPARGKCNJ6KCNJ5KCNJ3PTGDR2 | |
| SCHEMBL3204752 | 0.72 | PPARG (0.54) | PPARGFAAHKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL3204742 | 0.72 | PPARG (0.54) | PPARGFAAHKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL3220124 | 0.72 | PPARG (0.51) | PPARGKCNJ6KCNJ5KCNJ3PTGDR2 | |
| SCHEMBL27737192 | 0.70 | PPARG (0.63) | PPARGKCNJ6KCNJ5KCNJ3PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |