Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794043 | 0.84 | PRCP (0.51) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL17375666 | 0.84 | PRCP (0.51) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL17375664 | 0.84 | PRCP (0.51) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL373560 | 0.83 | PRCP (0.43) | PRCPDPP7KDM4ECYP3A4CYP2D6 | |
| SCHEMBL7299117 | 0.83 | PRCP (0.43) | PRCPDPP7KDM4ECYP3A4CYP2D6 | |
| SCHEMBL28232408 | 0.83 | PRCP (0.43) | PRCPDPP7KDM4ECYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL28132269 | 0.82 | PRCP (0.50) | PRCPDPP7TLR2HTR2CHTR2B | |
| SCHEMBL3862863 | 0.81 | PRCP (0.50) | PRCPDPP7KDM4ETLR2HTR2C | |
| SCHEMBL809691 | 0.81 | PRCP (0.50) | PRCPDPP7KDM4ETLR2HTR2C | |
| SCHEMBL3862861 | 0.81 | PRCP (0.50) | PRCPDPP7KDM4ETLR2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912662-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007016364-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |