⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680526 | 0.80 | — | — | |
| SCHEMBL1680615 | 0.77 | — | — | |
| SCHEMBL1680480 | 0.74 | — | — | |
| SCHEMBL6483604 | 0.74 | — | — | |
| SCHEMBL269126 | 0.74 | — | — | |
| SCHEMBL29857 | 0.74 | — | — | |
| SCHEMBL1680479 | 0.74 | — | — | |
| SCHEMBL577440 | 0.74 | — | — | |
| SCHEMBL1680475 | 0.74 | — | — | |
| SCHEMBL5333184 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339570-A1 | BICYCLIC DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2020-10-29 | — | — | US | claimed |
| EP-2900669-B1 | HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AND RELATED COMPOUNDS AS AUTOTAXIN (ATX) INHIBITORS AND AS INHIBITORS OF THE LYSOPHOSPHATIDIC ACID (LPA) PRODUCTION FOR TREATING E.G. RENAL DISEASES | HOFFMANN LA ROCHE (CH) | 2019-09-04 | — | — | EP | claimed |
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | claimed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | claimed |
| US-20180118741-A1 | NEW BICYCLIC DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2018-05-03 | — | — | US | claimed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| US-20170050960-A1 | NEW BICYCLIC DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2017-02-23 | — | — | US | claimed |
| CN-104910177-B | Aminomethyl triazole-substituted tricyclic fluoroquinolone carboxylic acid derivative and preparation method and application thereof | 河南大学 | 2017-02-22 | — | — | CN | claimed |
| CN-104817572-B | Chiral aminomethyl aminomethyl triazole substituted tricyclic fluoroquinolone carboxylic acid derivative and preparation method and applications thereof | 河南大学 | 2017-02-01 | — | — | CN | claimed |
| US-9458193-B1 | Proline compounds as Granzyme B inhibitors | VIDA THERAPEUTICS INC. (CA) | 2016-10-04 | — | — | US | claimed |
| CN-104910177-A | Aminomethyl triazole-substituted tricyclic fluoroquinolone carboxylic acid derivative and preparation method and application thereof | UNIV HENAN | 2015-09-16 | — | — | CN | claimed |
| CN-104876909-A | Aminomethyltriazole substituted polyfluoroquinolone carboxylic acid derivative as well as preparation method and application of derivative | UNIV HENAN | 2015-09-02 | — | — | CN | claimed |
| EP-2900669-A1 | NEW BICYCLIC DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2015-08-05 | — | — | EP | claimed |
| CN-104817572-A | Chiral aminomethyl aminomethyl triazole substituted tricyclic fluoroquinolone carboxylic acid derivative and preparation method and applications thereof | UNIV HENAN | 2015-08-05 | — | — | CN | claimed |
| CN-104803975-A | Aminomethyl triazole-substituted difluoroquinolone carboxylic acid type derivative as well as preparation method and application thereof | UNIV HENAN | 2015-07-29 | — | — | CN | claimed |
| WO-2015036312-A1 | AQUEOUS FORMULATION FOR THE CLEANING OF HARD SURFACES | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2015-03-19 | — | — | WO | claimed |
| EP-1092788-B1 | Corrosion inhibiting compositions | BRAD CHEM TECHNOLOGY LTD (GB) | 2010-08-11 | — | — | EP | claimed |
| US-6984340-B1 | Corrosion inhibiting formulations | BRAD-CHEM TECHNOLOGY LIMTIED (GB) | 2006-01-10 | — | — | US | claimed |
| EP-1092788-A2 | Corrosion inhibiting compositions | Brad-Chem Technology Ltd. (GB) | 2001-04-18 | — | — | EP | claimed |
| EP-0610155-A1 | Stabilized polyamide compositions | CIBA-GEIGY AG (CH) | 1994-08-10 | — | — | EP | claimed |