Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511479 | 0.81 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL28967373 | 0.76 | MAPK1 (0.33) | NPC1RAB9A | |
| SCHEMBL30137556 | 0.76 | MAPK1 (0.33) | NPC1RAB9A | |
| SCHEMBL21132564 | 0.70 | NPC1 (0.35) | NPC1RAB9A | |
| SCHEMBL28996428 | 0.66 | — | — | |
| SCHEMBL25004287 | 0.66 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL31148642 | 0.66 | KMT2A (0.35) | NPC1RAB9A | |
| SCHEMBL31148580 | 0.66 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL25207863 | 0.64 | — | — | |
| SCHEMBL25204833 | 0.64 | TARBP2 (0.38) | GLP1RNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893585-A1 | PROCESS FOR THE PREPARATION OF N-[4-(4-FLUOROPHENYL)-5-FORMYL-6-ISOPROPYL-PYRIMIDIN-2-YL]-N-METHYLMETHANESULFONAMIDE | Fermion Oy (FI) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128954-A1 | PROCESS FOR THE PREPARATION OF N-[4-(4-FLUOROPHENYL)-5-FORMYL-6-ISOPROPYL-PYRIMIDIN-2-YL]-N-METHYLMETHANESULFONAMIDE | FERMION OY (FI) | 2006-12-07 | — | — | WO | disclosed |