Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613874 | 0.80 | MRGPRX4 (0.65) | MRGPRX4MAOBFFAR4FFAR1 | |
| SCHEMBL30344886 | 0.79 | MAOB (0.69) | MAOBFFAR4FFAR1GPR34SMN1; SMN2 | |
| SCHEMBL538272 | 0.79 | MAOB (0.69) | MAOBFFAR4FFAR1GPR34SMN1; SMN2 | |
| SCHEMBL1439758 | 0.78 | PPARD (0.58) | MRGPRX4MAOBFFAR4FFAR1PPARG | |
| SCHEMBL1437459 | 0.78 | MAOB (0.52) | MRGPRX4MAOBFFAR4FFAR1PPARG | |
| SCHEMBL70797 | 0.77 | MAOB (0.60) | MRGPRX4MAOBMAPTMAPK1TDP1 | |
| SCHEMBL18165808 | 0.76 | PDE4A (0.48) | PPARGMAPTL3MBTL1SMN1; SMN2AR | |
| SCHEMBL1437002 | 0.75 | MAOB (0.56) | MRGPRX4MAOBFFAR4FFAR1PPARG | |
| SCHEMBL1248693 | 0.75 | MAOB (0.66) | MRGPRX4MAOBFFAR4FFAR1GPR34 | |
| SCHEMBL3758682 | 0.74 | MAOB (0.61) | MRGPRX4MAOBFFAR1SMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| EP-1697304-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054176-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | MRGPRX4 1752/4885MAOB 4323/4885FFAR4 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.